RAF Typhoon FGR4s have operated alongside France's air force in a combined operation targeting an hidden munitions depot in Syrian territory employed by the Islamic State group (IS), per a report from the British defence ministry.
The facility, identified by surveillance, was thought to be housing weapons and explosive materials, the announcement noted, and was located in hills just north of the historic site of Palmyra in the heart of Syria.
"The RAF jets utilized laser-guided Paveway IV weapons to hit a several entry passages leading to the depot... initial indications indicate the objective was successfully hit," the ministry announced.
There was no evidence of any civilian impact in the strike on Saturday evening and each participating jet returned safely, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
Daesh - also known as the so-called Islamic State - established militant control over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This operation shows the UK's leading role, and commitment to work closely with our partners, to stamp out any revival of the terrorist group and their dangerous and violent ideologies in the area," the British Defence Secretary the minister stated.
RAF aircraft have conducted patrols over Syrian airspace to "prevent any efforts to regroup" of the group after its military defeat at the battle of Baghuz in 2019, the MoD reported.
"I extend gratitude to every member of our armed forces involved in this operation for their skill and their bravery," Healey added. "They were among thousands of British troops stationed over Christmas and New Year. This operation, to eliminate militants who pose a risk to our security, demonstrates how UK forces are prepared to act, throughout the year, protecting the UK domestically and influential overseas."
Last December, the United States armed forces carried out what it termed a "massive strike" targeting Islamic State objectives in Syria, after an ambush claimed the lives of two US servicemembers and a civilian interpreter in Palmyra.
The UN reports IS still boasts an estimated 5,000 to 7,000 fighters in both countries.